20 April 2019 Blog Post: "Any opinions on the science behind this food allergy test or others like it?"

A patient direct messaged me the following: “Any opinions on the science behind this food allergy test or others like it?”
 

My answer: Who needs an opinion when there are data! A fast click on the link reveals the method used in this testing protocol – namely “IgG Reactivity to 96 Foods.” Turning to the evidence… There are several validated, standardized, and accepted tests for the evaluation of food allergy and intolerance. However, there are also a large number of other tests for these conditions that are promoted by various laboratories and practitioners who are not allergy specialists [Kelso JM, 2018]. The clinical utility of food-specific IgG tests has not been established, a fact that even some laboratories performing these assays acknowledge. A position statement from the European Academy of Allergy and Clinical Immunology (EAACI) concludes “food-specific IgG4 does not indicate (imminent) food allergy or intolerance, but rather a physiological response of the immune system after exposition to food components. Therefore, testing of IgG4 to foods is considered as irrelevant for the laboratory work-up of food allergy or intolerance and should not be performed in case of food-related complaints” [Stapel SO et al, 2008]. So… the $159 is probably better spent elsewhere.

𝗦𝗶𝗴𝗻 𝗨𝗽 𝗳𝗼𝗿 𝗢𝘂𝗿 𝗡𝗲𝘄𝘀𝗹𝗲𝘁𝘁𝗲𝗿

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