3 September 2018 Blog Post: New Research in August on "Baby" Aspirin
When considering all cardiovascular events combined, a daily aspirin showed no significant effect. The primary endpoint occurred in 269 (4.29%) individuals in the aspirin group versus 281 (4.48%) in the placebo group.
Of interest, aspirin did reduce the risk of total and nonfatal heart attacks. Aspirin accounted for an 82.1% reduction in these events for those aged 50-59 years of age and and a 54.3% reduction in the 59-69 age group. There was no effect of aspirin use on risk of stroke.
Bleeding was relatively infrequent, and when it occurred, was mild and most commonly from the GI tract – 61 (0.97%) individuals in the aspirin group versus 29 (0.46%) in the placebo group. Other commonly reported side effects of aspirin were indigestion, nosebleeds, gastroesophageal reflux disease, and upper abdominal pain.
So it looks as if I will need to amend my “desert island” advice to exclude any risk reduction in stroke. And 1% of you may get a GI or nose bleed falling out of the coconut tree…
In an equally fascinating study published earlier in the month, Canadian researchers suggested that a low dose daily aspirin could reduce HIV susceptibility. So the aspirin story continues on – a century after becoming available.
𝗦𝗶𝗴𝗻 𝗨𝗽 𝗳𝗼𝗿 𝗢𝘂𝗿 𝗡𝗲𝘄𝘀𝗹𝗲𝘁𝘁𝗲𝗿
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